Project Coordinator and Project aims
The project aims at putting together and integrating the different skills of researchers and clinicians working at the Department of Medical Sciences in the fields of health, “omics” and “big data” analyses in order to harmonize and optimize methods and processes, and to significantly improve the knowledge on disease mechanisms. This approach will allow a meaningful step forward in health care, patient management and personalized medicine.
The major areas involved in the project are cardio-metabolics, medical genetics and pharmacogenomics, solid organs transplantation and oncology
Specific aims of the project are:
High-throughput analyses on recruited cohorts of patients, to define genomic, proteomic and metabolic profiles to better understand pathogenetic mechanisms underlying diseases onset and progression
Development of predictive algorithms to estimate risks and clinical outcomes, instrumental to improve diagnosis and prognosis
Identification of novel biomarkers in recruited cohorts of patients, well characterized from the phenotypic and clinical point of view, to be used in a translational perspective
Design of tailored diagnostic and therapeutic interventions towards a personalized medicine